Tissue and cellular mechanics

Here we aim to understand how physical properties of cells like shape, stiffness or adhesiveness are important not only to shape a cell but the tissue as a whole and what is the molecular machinery behind that. Together with physicists and mathematicians we attempt to generate biophysical models that mimic tissues i.e. the epidermis, as a mechanical continuums and ask how specific differences in cellular mechanics affect tissue formation and how in turn single cell behavior is ruled by patterns of tissue mechanics.

Dr Matthias Rübsam

Aishwarya Bhosale