Tissue and cellular mechanics
Here we aim to understand how physical properties of cells like shape, stiffness or adhesiveness are important not only to shape a cell but the tissue as a whole and what is the molecular machinery behind that. Together with physicists and mathematicians we attempt to generate biophysical models that mimic tissues i.e. the epidermis, as a mechanical continuums and ask how specific differences in cellular mechanics affect tissue formation and how in turn single cell behavior is ruled by patterns of tissue mechanics.
Dr Matthias Rübsam